What is ghb
It is taken orally and is frequently combined with alcohol. This enzyme appears to be induced by cAMP levels,  meaning substances that elevate cAMP, such as forskolin and vinpocetinemay increase GHB synthesis and release.
This is the law that made GHB a Schedule 1 controlled substance. However, when GHB is consumed for recreational or health promotion purposes, its concentration in the body is much higher than normal, which changes the enzyme kinetics so that these pathways operate to metabolise GHB rather than producing it.
GHB use can kill. GHB became known to the general public as a date rape drug by the late s.
Withdrawal and treatment Getting help: Treatment In Australia, there are many different types of treatments for drug problems. When mixed with alcohol, it has a depressant effect that can cause someone to black out. Conversely, endogeneous GHB production in those taking valproic acid will be inhibited via inhibition of the conversion from succinic acid semialdehyde to GHB. At higher doses, GHB may induce nausea , dizziness , drowsiness , agitation , visual disturbances, depressed breathing , amnesia , unconsciousness , and death. This means that victims may not be able to resist or recall a sexual assault. GHB use can kill. The naturally-occurring metabolite GHB is present in much lower concentrations in the brain than those levels found when the drug is abused. This is why GHB is often called the date rape drug. Sodium oxybate is also used therapeutically in Italy under the brand name Alcover for treatment of alcohol withdrawal and dependence. Medical use[ edit ] The only common medical use for GHB today are in the treatment of narcolepsy  and more rarely alcoholism   but its use for alcoholism is not supported by evidence from randomized controlled trials. In moderate amounts, GHB can produce feelings of: relaxation. Pregnancy and breastfeeding Read about the effects of drugs on pregnancy and breastfeeding. One potential cause of death from GHB consumption is polydrug toxicity. It was also widely available in the s as a dietary supplement and bodybuilding product.
Because of its serious effects, GHB has led to emergency medical care for many young people and has killed more users than the drug Ecstasy. Sodium oxybate is also used therapeutically in Italy under the brand name Alcover for treatment of alcohol withdrawal and dependence.
It is a Schedule III controlled substance, and requires patient enrollment in a restricted access program. Side effects of GHB can include drowsiness, amnesia and impaired movement and speech, as well as more serious symptoms of agitation, unconsciousness and respiratory collapse.
People who take GHB may become unconscious pass outstop breathing, and go into a coma.
GHB is an agonist at the newly characterized[ when? This may explain the respiratory arrest that has been reported after ingestion of both drugs.
based on 29 review